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Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switch

Despite the extensive use of zebrafish as a model organism in developmental biology and regeneration research, genetic techniques enabling conditional analysis of gene function are limited. In this study, we generated Zwitch, a Cre-dependent invertible gene-trap cassette, enabling the establishment...

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Detalles Bibliográficos
Autores principales: Sugimoto, Kotaro, Hui, Subhra P, Sheng, Delicia Z, Kikuchi, Kazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435461/
https://www.ncbi.nlm.nih.gov/pubmed/28513431
http://dx.doi.org/10.7554/eLife.24635