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Rapid evolution of the human mutation spectrum

DNA is a remarkably precise medium for copying and storing biological information. This high fidelity results from the action of hundreds of genes involved in replication, proofreading, and damage repair. Evolutionary theory suggests that in such a system, selection has limited ability to remove gen...

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Detalles Bibliográficos
Autores principales: Harris, Kelley, Pritchard, Jonathan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435464/
https://www.ncbi.nlm.nih.gov/pubmed/28440220
http://dx.doi.org/10.7554/eLife.24284