Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase

Obesity-associated insulin resistance plays a central role in type 2 diabetes. As such, tyrosine phosphatases that dephosphorylate the insulin receptor (IR) are potential therapeutic targets. The low molecular weight protein tyrosine phosphatase (LMPTP) is a proposed IR phosphatase, yet its role in...

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Detalles Bibliográficos
Autores principales: Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R., Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A., Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas DY, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
https://www.ncbi.nlm.nih.gov/pubmed/28346406
http://dx.doi.org/10.1038/nchembio.2344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
https://www.ncbi.nlm.nih.gov/pubmed/28346406
http://dx.doi.org/10.1038/nchembio.2344

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