Cargando…
Impact of heme on specific antibody production in mice: promotive, inhibitive or null outcome is determined by its concentration
Free heme is an endogenous danger signal that provokes innate immunity. Active innate immunity provides a precondition of an effective adaptive immune response. However, heme catabolites, CO, biliverdin and bilirubin trigger immunosuppression. Furthermore, free heme induces expression of heme oxygen...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435615/ https://www.ncbi.nlm.nih.gov/pubmed/28560357 http://dx.doi.org/10.1016/j.heliyon.2017.e00303 |