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Metabolomic analysis shows differential hepatic effects of T(2) and T(3) in rats after short-term feeding with high fat diet

Nonalcoholic fatty liver disease (NAFLD) is a major health problem worldwide, and is often associated with lipotoxic injury, defective mitochondrial function, and insulin resistance. Thyroid hormones (THs) are important regulators of hepatic lipid metabolism. Among the THs, diiodothyronine (T(2)) an...

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Detalles Bibliográficos
Autores principales: Iannucci, Liliana F., Cioffi, Federica, Senese, Rosalba, Goglia, Fernando, Lanni, Antonia, Yen, Paul M., Sinha, Rohit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435676/
https://www.ncbi.nlm.nih.gov/pubmed/28515456
http://dx.doi.org/10.1038/s41598-017-02205-1