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Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases

Owing to the key role of trehalose in pathogenic organisms, there has recently been growing interest in trehalose metabolism for therapeutic purposes. Trehalose-6-phosphate phosphatase (TPP) is a pivotal enzyme in the most prominent biosynthesis pathway (OtsAB). Here, we compare the enzyme character...

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Detalles Bibliográficos
Autores principales: Cross, Megan, Rajan, Siji, Chekaiban, Janine, Saunders, Jake, Hamilton, Chloe, Kim, Jeong-Sun, Coster, Mark J., Gasser, Robin B., Hofmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435700/
https://www.ncbi.nlm.nih.gov/pubmed/28515463
http://dx.doi.org/10.1038/s41598-017-02220-2