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No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma

The intronic microRNA (miR)-342 has been proposed as a potent tumor-suppressor gene. miR-342 is found to be downregulated or epigenetically silenced in multiple different tumor sites, and this loss of expression permits the upregulation of several key oncogenic pathways. In several different cell li...

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Detalles Bibliográficos
Autores principales: Dooley, James, Lagou, Vasiliki, Pasciuto, Emanuela, Linterman, Michelle A., Prosser, Haydn M., Himmelreich, Uwe, Liston, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435746/
https://www.ncbi.nlm.nih.gov/pubmed/28573106
http://dx.doi.org/10.3389/fonc.2017.00101