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RegA Plays a Key Role in Oxygen-Dependent Establishment of Persistence and in Isocitrate Lyase Activity, a Critical Determinant of In vivo Brucella suis Pathogenicity

For aerobic human pathogens, adaptation to hypoxia is a critical factor for the establishment of persistent infections, as oxygen availability is low inside the host. The two-component system RegB/A of Brucella suis plays a central role in the control of respiratory systems adapted to oxygen deficie...

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Detalles Bibliográficos
Autores principales: Abdou, Elias, Jiménez de Bagüés, María P., Martínez-Abadía, Ignacio, Ouahrani-Bettache, Safia, Pantesco, Véronique, Occhialini, Alessandra, Al Dahouk, Sascha, Köhler, Stephan, Jubier-Maurin, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435760/
https://www.ncbi.nlm.nih.gov/pubmed/28573107
http://dx.doi.org/10.3389/fcimb.2017.00186