Impaired Autophagy and Defective T Cell Homeostasis in Mice with T Cell-Specific Deletion of Receptor for Activated C Kinase 1

Autophagy plays a central role in maintaining T cell homeostasis. Our previous study has shown that hepatocyte-specific deficiency of receptor for activated C kinase 1 (RACK1) leads to lipid accumulation in the liver, accompanied by impaired autophagy, but its in vivo role in T cells remains unclear...

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Detalles Bibliográficos
Autores principales: Qiu, Guihua, Liu, Jian, Cheng, Qianqian, Wang, Qingyang, Jing, Zhaofei, Pei, Yujun, Zhao, Min, Wang, Jing, Guo, Jessie Yanxiang, Zhang, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435764/
https://www.ncbi.nlm.nih.gov/pubmed/28572806
http://dx.doi.org/10.3389/fimmu.2017.00575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435764/
https://www.ncbi.nlm.nih.gov/pubmed/28572806
http://dx.doi.org/10.3389/fimmu.2017.00575

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