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Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt
Osteoclasts are giant bone cells formed by fusion from monocytes and uniquely capable of a complete destruction of mineralized tissues. Previously, we have demonstrated that in energy-rich environment not only osteoclast fusion index (the number of nuclei each osteoclast contains), but also cytoplas...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435769/ https://www.ncbi.nlm.nih.gov/pubmed/28573133 http://dx.doi.org/10.3389/fcell.2017.00054 |