3′ Uridylation controls mature microRNA turnover during CD4 T-cell activation

Activation of T lymphocytes requires a tight regulation of microRNA (miRNA) expression. Terminal uridyltransferases (TUTases) catalyze 3′ nontemplated nucleotide addition (3′NTA) to miRNAs, which may influence miRNA stability and function. Here, we investigated 3′NTA to mature miRNA in CD4 T lymphoc...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Vázquez, Cristina, Enright, Anton J., Rodríguez-Galán, Ana, Pérez-García, Arantxa, Collier, Paul, Jones, Matthew R., Benes, Vladimir, Mizgerd, Joseph P., Mittelbrunn, María, Ramiro, Almudena R., Sánchez-Madrid, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435861/
https://www.ncbi.nlm.nih.gov/pubmed/28351886
http://dx.doi.org/10.1261/rna.060095.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435861/
https://www.ncbi.nlm.nih.gov/pubmed/28351886
http://dx.doi.org/10.1261/rna.060095.116

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