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A new cis-acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization

Spinal muscular atrophy (SMA) is caused by mutations and/or deletions of the survival motor neuron gene (SMN1). Besides its function in the biogenesis of spliceosomal snRNPs, SMN might possess a motor neuron specific role and could function in the transport of axonal mRNAs and in the modulation of l...

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Detalles Bibliográficos
Autores principales: Rihan, Khalil, Antoine, Etienne, Maurin, Thomas, Bardoni, Barbara, Bordonné, Rémy, Soret, Johann, Rage, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435863/
https://www.ncbi.nlm.nih.gov/pubmed/28258160
http://dx.doi.org/10.1261/rna.056788.116