A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

The eukaryotic translation initiation factor eIF4E acts in the nuclear export and translation of a subset of mRNAs. Both of these functions contribute to its oncogenic potential. While the biochemical mechanisms that underlie translation are relatively well understood, the molecular basis for eIF4E&...

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Detalles Bibliográficos
Autores principales: Volpon, Laurent, Culjkovic-Kraljacic, Biljana, Sohn, Hye Seon, Blanchet-Cohen, Alexis, Osborne, Michael J., Borden, Katherine L.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435865/
https://www.ncbi.nlm.nih.gov/pubmed/28325843
http://dx.doi.org/10.1261/rna.060137.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435865/
https://www.ncbi.nlm.nih.gov/pubmed/28325843
http://dx.doi.org/10.1261/rna.060137.116

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