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A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery
The eukaryotic translation initiation factor eIF4E acts in the nuclear export and translation of a subset of mRNAs. Both of these functions contribute to its oncogenic potential. While the biochemical mechanisms that underlie translation are relatively well understood, the molecular basis for eIF4E&...
Autores principales: | Volpon, Laurent, Culjkovic-Kraljacic, Biljana, Sohn, Hye Seon, Blanchet-Cohen, Alexis, Osborne, Michael J., Borden, Katherine L.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435865/ https://www.ncbi.nlm.nih.gov/pubmed/28325843 http://dx.doi.org/10.1261/rna.060137.116 |
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