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Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells

Faithful resetting of the epigenetic memory of a somatic cell to a pluripotent state during cellular reprogramming requires DNA methylation to silence somatic gene expression and dynamic DNA demethylation to activate pluripotency gene transcription. The removal of methylated cytosines requires the b...

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Detalles Bibliográficos
Autores principales:	Ho, Jaclyn J., Cattoglio, Claudia, McSwiggen, David T., Tjian, Robert, Fong, Yick W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435894/ https://www.ncbi.nlm.nih.gov/pubmed/28512237 http://dx.doi.org/10.1101/gad.295741.116

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