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The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis

In eukaryotes, the synthesis of ribosomal subunits, which involves the maturation of the ribosomal (r)RNAs and assembly of ribosomal proteins, requires the co-ordinated action of a plethora of ribosome biogenesis factors. Many of these cofactors remain to be characterized in human cells. Here, we de...

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Detalles Bibliográficos
Autores principales: Memet, Indira, Doebele, Carmen, Sloan, Katherine E., Bohnsack, Markus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435916/
https://www.ncbi.nlm.nih.gov/pubmed/28115624
http://dx.doi.org/10.1093/nar/gkx013