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Designed Spiroketal Protein Modulation

Spiroketals are structural motifs found in many biologically active natural products, which has stimulated considerable efforts toward their synthesis and interest in their use as drug lead compounds. Despite this, the use of spiroketals, and especially bisbenzanulated spiroketals, in a structure‐ba...

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Detalles Bibliográficos
Autores principales: Scheepstra, Marcel, Andrei, Sebastian A., Unver, M. Yagiz, Hirsch, Anna K. H., Leysen, Seppe, Ottmann, Christian, Brunsveld, Luc, Milroy, Lech‐Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435924/
https://www.ncbi.nlm.nih.gov/pubmed/28407400
http://dx.doi.org/10.1002/anie.201612504