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Achieving large dynamic range control of gene expression with a compact RNA transcription–translation regulator

RNA transcriptional regulators are emerging as versatile components for genetic network construction. However, these regulators suffer from incomplete repression in their OFF state, making their dynamic range less than that of their protein counterparts. This incomplete repression causes expression...

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Detalles Bibliográficos
Autores principales: Westbrook, Alexandra M., Lucks, Julius B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435934/
https://www.ncbi.nlm.nih.gov/pubmed/28387839
http://dx.doi.org/10.1093/nar/gkx215