Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation

Background: Claspin and TopBP1 are checkpoint mediators that are required for the phosphorylation of Chk1 by ATR to maintain genomic stability. Here, we investigated the functions of Drosophila Claspin and mus101 (TopBP1 ortholog) during chorion (eggshell component) gene amplification, which occurs...

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Detalles Bibliográficos
Autores principales: Choi, Seung Ho, Park, Ji‐Hong, Nguyen, Tram Thi Ngoc, Shim, Hee Jin, Song, Young‐Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435936/
https://www.ncbi.nlm.nih.gov/pubmed/28294450
http://dx.doi.org/10.1002/dvdy.24499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435936/
https://www.ncbi.nlm.nih.gov/pubmed/28294450
http://dx.doi.org/10.1002/dvdy.24499

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