Precise quantification of translation inhibition by mRNA structures that overlap with the ribosomal footprint in N-terminal coding sequences

A mRNA's translation rate is controlled by several sequence determinants, including the presence of RNA structures within the N-terminal regions of its coding sequences. However, the physical rules that govern when such mRNA structures will inhibit translation remain unclear. Here, we introduce...

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Detalles Bibliográficos
Autores principales: Espah Borujeni, Amin, Cetnar, Daniel, Farasat, Iman, Smith, Ashlee, Lundgren, Natasha, Salis, Howard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435973/
https://www.ncbi.nlm.nih.gov/pubmed/28158713
http://dx.doi.org/10.1093/nar/gkx061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435973/
https://www.ncbi.nlm.nih.gov/pubmed/28158713
http://dx.doi.org/10.1093/nar/gkx061

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