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Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells

The anti-inflammatory effects of statins (HMG-CoA reductase inhibitors) within the cardiovascular system are well-established; however, their neuroinflammatory potential is unclear. It is currently unknown whether statins' neurological effects are lipid-dependent or due to pleiotropic mechanism...

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Detalles Bibliográficos
Autores principales: McFarland, A. J., Davey, A. K., Anoopkumar-Dukie, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435995/
https://www.ncbi.nlm.nih.gov/pubmed/28546657
http://dx.doi.org/10.1155/2017/2582745