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Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation

Myrf is a key transcription factor for oligodendrocyte differentiation and central nervous system myelination. We and others have previously shown that Myrf is generated as a membrane protein in the endoplasmic reticulum (ER), and that it undergoes auto-processing to release its N-terminal fragment...

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Detalles Bibliográficos
Autores principales: Kim, Dongkyeong, Choi, Jin-ok, Fan, Chuandong, Shearer, Randall S., Sharif, Mohamed, Busch, Patrick, Park, Yungki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436001/
https://www.ncbi.nlm.nih.gov/pubmed/28160598
http://dx.doi.org/10.1093/nar/gkx080