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Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation
Myrf is a key transcription factor for oligodendrocyte differentiation and central nervous system myelination. We and others have previously shown that Myrf is generated as a membrane protein in the endoplasmic reticulum (ER), and that it undergoes auto-processing to release its N-terminal fragment...
Autores principales: | Kim, Dongkyeong, Choi, Jin-ok, Fan, Chuandong, Shearer, Randall S., Sharif, Mohamed, Busch, Patrick, Park, Yungki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436001/ https://www.ncbi.nlm.nih.gov/pubmed/28160598 http://dx.doi.org/10.1093/nar/gkx080 |
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