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EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Following gut epithelial damage, epidermal growth factor receptor/mitogen-activated protein kinase (EGFR/MAPK) signalling triggers Drosophila intestinal stem cells to produce enteroblasts (EBs) and enterocytes (ECs) that regenerate the gut. As EBs differentiate into ECs, they become postmitotic, but...
Autores principales: | Xiang, Jinyi, Bandura, Jennifer, Zhang, Peng, Jin, Yinhua, Reuter, Hanna, Edgar, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436070/ https://www.ncbi.nlm.nih.gov/pubmed/28485389 http://dx.doi.org/10.1038/ncomms15125 |
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