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Periostin-Binding DNA Aptamer Treatment Ameliorates Peritoneal Dialysis-Induced Peritoneal Fibrosis

Peritoneal fibrosis is a major complication in peritoneal dialysis (PD) patients, which leads to dialysis discontinuation. Periostin, increased by transforming growth factor β1 (TGF-β1) stimulation, induces the expression of extracellular matrix (ECM) genes. Aberrant periostin expression has been de...

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Detalles Bibliográficos
Autores principales: Nam, Bo Young, Park, Jung Tak, Kwon, Young Eun, Lee, Jung Pyo, Jung, Jong Ha, Kim, Youndong, Kim, Seonghun, Park, Jimin, Um, Jae Eun, Wu, Meiyan, Han, Seung Hyeok, Yoo, Tae-Hyun, Kang, Shin-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436072/
https://www.ncbi.nlm.nih.gov/pubmed/28624215
http://dx.doi.org/10.1016/j.omtn.2017.05.001