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Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse

Obesity and diabetes are independent risk factors for heart failure and are associated with the consumption of diet rich in saturated fat and sugar, Western diet (WD), known to induce cardiac dysfunction in the mouse through incompletely characterized inflammatory mechanisms. We hypothesized that th...

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Detalles Bibliográficos
Autores principales: Carbone, S, Lee, P J H, Mauro, A G, Mezzaroma, E, Buzzetti, R, Van Tassell, B, Abbate, A, Toldo, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436096/
https://www.ncbi.nlm.nih.gov/pubmed/28394363
http://dx.doi.org/10.1038/nutd.2017.1