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Differences between germline and somatic mutation rates in humans and mice

The germline mutation rate has been extensively studied and has been found to vary greatly between species, but much less is known about the somatic mutation rate in multicellular organisms, which remains very difficult to determine. Here, we present data on somatic mutation rates in mice and humans...

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Detalles Bibliográficos
Autores principales: Milholland, Brandon, Dong, Xiao, Zhang, Lei, Hao, Xiaoxiao, Suh, Yousin, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436103/
https://www.ncbi.nlm.nih.gov/pubmed/28485371
http://dx.doi.org/10.1038/ncomms15183