Berberine activates AMPK to suppress proteolytic processing, nuclear translocation and target DNA binding of SREBP-1c in 3T3-L1 adipocytes

AMP-activated protein kinase (AMPK) and sterol regulatory element binding protein (SREBP)-1c are major therapeutic targets in the treatment of metabolic diseases. In the present study, the fat-reducing mechanisms of berberine (BBR), a natural isoquinoline, was investigated by examining the AMPK-medi...

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Detalles Bibliográficos
Autores principales: Jang, Jaewoong, Jung, Yoonju, Seo, Seong Jun, Kim, Seok-Min, Shim, Yae Jie, Cho, Soo Hyun, Chung, Sang-In, Yoon, Yoosik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436149/
https://www.ncbi.nlm.nih.gov/pubmed/28487951
http://dx.doi.org/10.3892/mmr.2017.6513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436149/
https://www.ncbi.nlm.nih.gov/pubmed/28487951
http://dx.doi.org/10.3892/mmr.2017.6513

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