Sulforaphane prevents bleomycin-induced pulmonary fibrosis in mice by inhibiting oxidative stress via nuclear factor erythroid 2-related factor-2 activation

Lung fibrosis is associated with inflammation, apoptosis and oxidative damage. The transcription factor nuclear factor erythroid 2-related factor-2 (Nrf2) prevents damage to cells from oxidative stress by regulating the expression of antioxidant proteins. Sulforaphane (SFN), an Nrf2 activator, addit...

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Detalles Bibliográficos
Autores principales: Yan, Bingdi, Ma, Zhongsen, Shi, Shaomin, Hu, Yuxin, Ma, Tiangang, Rong, Gao, Yang, Junling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436151/
https://www.ncbi.nlm.nih.gov/pubmed/28487960
http://dx.doi.org/10.3892/mmr.2017.6546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436151/
https://www.ncbi.nlm.nih.gov/pubmed/28487960
http://dx.doi.org/10.3892/mmr.2017.6546

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