Azidothymidine inhibits cell growth and telomerase activity and induces DNA damage in human esophageal cancer

Esophageal cancer is one of the most common type of malignancies. Telomerase activity, which is absent or weakly detected in the majority of human somatic cells, is elevated in esophageal cancer. Although azidothymidine (AZT), a reverse transcriptase inhibitor, has been utilized as a treatment for t...

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Detalles Bibliográficos
Autores principales: Wang, Haoli, Zhou, Jianwen, He, Qiong, Dong, Yu, Liu, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436214/
https://www.ncbi.nlm.nih.gov/pubmed/28487971
http://dx.doi.org/10.3892/mmr.2017.6549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436214/
https://www.ncbi.nlm.nih.gov/pubmed/28487971
http://dx.doi.org/10.3892/mmr.2017.6549

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