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Azidothymidine inhibits cell growth and telomerase activity and induces DNA damage in human esophageal cancer
Esophageal cancer is one of the most common type of malignancies. Telomerase activity, which is absent or weakly detected in the majority of human somatic cells, is elevated in esophageal cancer. Although azidothymidine (AZT), a reverse transcriptase inhibitor, has been utilized as a treatment for t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436214/ https://www.ncbi.nlm.nih.gov/pubmed/28487971 http://dx.doi.org/10.3892/mmr.2017.6549 |