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Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma

Renal cell carcinoma (RCC) is the most common neoplasm of the kidney in adults, accounting for ~3% of adult malignancies. Understanding the underlying mechanism of RCC tumorigenesis is necessary to improve patient survival. The present study revealed that Taxol-induced microtubule (MT) polymerizatio...

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Detalles Bibliográficos
Autores principales: Ren, Yu, Wang, Xue, Lou, Zhongguan, Huang, Shuaishuai, Zhuang, Haihui, Wang, Yuduo, Weng, Guobin, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436224/
https://www.ncbi.nlm.nih.gov/pubmed/28487984
http://dx.doi.org/10.3892/mmr.2017.6543