Super Aqueous Solubility of Albendazole in β-Cyclodextrin for Parenteral Application in Cancer therapy

Poor aqueous solubility of anticancer drug, albendazole (ABZ), prevents parenteral application. Here, we demonstrate how to increase the aqueous solubility of ABZ to 6- 8 mg/ml using sulfobutylether - β-cyclodextrin (SBE-β-CD) or Hydroxypropyl- β-cyclodextrin (HP- β-CD) by manipulation of complexati...

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Detalles Bibliográficos
Autores principales: Pillai, Krishna, Akhter, Javed, Morris, David Lawson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436242/
https://www.ncbi.nlm.nih.gov/pubmed/28529602
http://dx.doi.org/10.7150/jca.17301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436242/
https://www.ncbi.nlm.nih.gov/pubmed/28529602
http://dx.doi.org/10.7150/jca.17301

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