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Effects of cytochrome P450 family 3 subfamily A member 5 gene polymorphisms on daunorubicin metabolism and adverse reactions in patients with acute leukemia

The present study aimed to investigate the association between the genetic polymorphism of cytochrome P450 family 3 subfamily A member 5 (CYP3A5) and the activity of CYP3A and plasma concentrations of daunorubicin (DNR) in patients with acute leukemia. A total of 36 children with newly diagnosed acu...

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Detalles Bibliográficos
Autores principales: Huang, Zhen, Wang, Juxiang, Qian, Jiangchao, Li, Yuan, Xu, Zhisheng, Chen, Min, Tong, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436286/
https://www.ncbi.nlm.nih.gov/pubmed/28440407
http://dx.doi.org/10.3892/mmr.2017.6470