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Constitutive androstane receptor activation promotes bilirubin clearance in a murine model of alcoholic liver disease

Increased plasma levels of bilirubin have been reported in rat models and patients with alcoholic liver disease (ALD). The constitutive androstane receptor (CAR) is a known xenobiotic receptor, which induces the detoxification and transport of bilirubin. In the present study, the bilirubin transport...

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Detalles Bibliográficos
Autores principales: Wang, Xiuyan, Zheng, Liyu, Wu, Jinming, Tang, Binbin, Zhang, Mengqin, Zhu, Debin, Lin, Xianfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436297/
https://www.ncbi.nlm.nih.gov/pubmed/28393244
http://dx.doi.org/10.3892/mmr.2017.6435