Cargando…

Constitutive androstane receptor activation promotes bilirubin clearance in a murine model of alcoholic liver disease

Increased plasma levels of bilirubin have been reported in rat models and patients with alcoholic liver disease (ALD). The constitutive androstane receptor (CAR) is a known xenobiotic receptor, which induces the detoxification and transport of bilirubin. In the present study, the bilirubin transport...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiuyan, Zheng, Liyu, Wu, Jinming, Tang, Binbin, Zhang, Mengqin, Zhu, Debin, Lin, Xianfan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436297/ https://www.ncbi.nlm.nih.gov/pubmed/28393244 http://dx.doi.org/10.3892/mmr.2017.6435

Ejemplares similares

Deletion of Constitutive Androstane Receptor Led to Intestinal Alterations and Increased Imidacloprid in Murine Liver
por: Sen, Anushna, et al.
Publicado: (2022)

β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor
por: Klag, Thomas, et al.
Publicado: (2018)

Signaling control of the constitutive androstane receptor (CAR)
por: Yang, Hui, et al.
Publicado: (2014)

Noncanonical Constitutive Androstane Receptor Signaling in Gene Regulation
por: Pustylnyak, Yuliya A., et al.
Publicado: (2020)

Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
por: Küblbeck, Jenni, et al.
Publicado: (2020)

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes
por: McMahon, Michael, et al.
Publicado: (2019)

Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression
por: Ahn, Hwa Young, et al.
Publicado: (2018)

β-catenin signaling, the constitutive androstane receptor and their mutual interactions
por: Braeuning, Albert, et al.
Publicado: (2020)

Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation
por: Juang, Shin-Hun, et al.
Publicado: (2020)

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
por: Lukowicz, Céline, et al.
Publicado: (2019)

Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium
por: López-Riera, Mireia, et al.
Publicado: (2021)

SAT017 Investigating The Spatial Regulation Mediated By Constitutive Androstane Receptor
por: Asokakumar, Anjana, et al.
Publicado: (2023)

Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis
por: Mathur, Bhoomika, et al.
Publicado: (2020)

Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation
por: Gao, Yue, et al.
Publicado: (2021)

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor
por: Lynch, Caitlin, et al.
Publicado: (2015)

Constitutive Androstane Receptor: A Peripheral and a Neurovascular Stress or Environmental Sensor
por: Oliviero, Fabiana, et al.
Publicado: (2020)

Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
por: Mathäs, Marianne, et al.
Publicado: (2014)

Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling
por: Li, Zhihui, et al.
Publicado: (2022)

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain
por: Skoda, Josef, et al.
Publicado: (2020)

SAT007 Excess Bile Acids Can Compensate To Promote Regeneration In Constitutive Androstane Receptor Knockout Mice
por: Zhou, Weinan, et al.
Publicado: (2023)

Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
por: Arnold, Katja A, et al.
Publicado: (2004)

Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor
por: Kanno, Yuichiro, et al.
Publicado: (2014)

Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
por: Lukowicz, Céline, et al.
Publicado: (2020)

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
Publicado: (2014)

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
por: Mathäs, Marianne, et al.
Publicado: (2016)

Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels
por: Hernandez, Juan P, et al.
Publicado: (2021)

Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells
por: Goedtke, Lisa, et al.
Publicado: (2020)

MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor
por: Shizu, Ryota, et al.
Publicado: (2012)

Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells
por: Chakraborty, S, et al.
Publicado: (2011)

Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis
por: Kim, Kang Ho, et al.
Publicado: (2018)

Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)
por: Cai, Xinran, et al.
Publicado: (2021)

RF03 | PMON287 Examining the role of Constitutive Androstane Receptor during Imidacloprid exposure
por: Sen, Anushna, et al.
Publicado: (2022)

Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha
por: Yueh, Mei-Fei, et al.
Publicado: (2012)

Correction: MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor
por: Shizu, Ryota, et al.
Publicado: (2013)

A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor
por: MacLeod, A. Kenneth, et al.
Publicado: (2013)

Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons
por: Thompson, Emma E, et al.
Publicado: (2005)

Antiproliferation of berberine is mediated by epigenetic modification of constitutive androstane receptor (CAR) metabolic pathway in hepatoma cells
por: Zhang, Lei, et al.
Publicado: (2016)

Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
por: Mejdrová, Ivana, et al.
Publicado: (2023)

Constitutive Androstane Receptor Agonist, TCPOBOP: Maternal Exposure Impairs the Growth and Development of Female Offspring in Mice
por: Pan, Shijia, et al.
Publicado: (2023)

Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation
por: Pinne, Marija, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nqf5u25lpjb3t3o2me3d2j1ikr