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Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study

The specific absorbed fraction (SAF) of energy is an essential element of internal dose assessment. Here reported a set of SAFs calculated for selected organs of a human voxel-based phantom. The Monte Carlo transport code GATE version 6.1 was used to simulate monoenergetic photons and electrons with...

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Autores principales: Asl, Ruhollah Ghahraman, Parach, Ali Asghar, Nasseri, Shahrokh, Momennezhad, Mehdi, Zakavi, Seyed Rasoul, Sadoughi, Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436316/
https://www.ncbi.nlm.nih.gov/pubmed/28553177
http://dx.doi.org/10.4103/1450-1147.203065
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author Asl, Ruhollah Ghahraman
Parach, Ali Asghar
Nasseri, Shahrokh
Momennezhad, Mehdi
Zakavi, Seyed Rasoul
Sadoughi, Hamid Reza
author_facet Asl, Ruhollah Ghahraman
Parach, Ali Asghar
Nasseri, Shahrokh
Momennezhad, Mehdi
Zakavi, Seyed Rasoul
Sadoughi, Hamid Reza
author_sort Asl, Ruhollah Ghahraman
collection PubMed
description The specific absorbed fraction (SAF) of energy is an essential element of internal dose assessment. Here reported a set of SAFs calculated for selected organs of a human voxel-based phantom. The Monte Carlo transport code GATE version 6.1 was used to simulate monoenergetic photons and electrons with energies ranging from 10 keV to 2 MeV. The particles were emitted from three source organs: kidneys, liver, and spleen. SAFs were calculated for three target regions in the body (kidneys, liver, and spleen) and compared with the results obtained using the MCNP4B and GATE/GEANT4 Monte Carlo codes. For most photon energies, the self-irradiation is higher, and the cross-irradiation is lower in the GATE results compared to the MCNP4B. The results show generally good agreement for photons and high-energy electrons with discrepancies within − 2% ±3%. Nevertheless, significant differences were found for cross-irradiation of photons of lower energy and electrons of higher energy due to statistical uncertainties larger than 10%. The comparisons of the SAF values for the human voxel phantom do not show significant differences, and the results also demonstrated the usefulness and applicability of GATE Monte Carlo package for voxel level dose calculations in nonuniform media. The present SAFs calculation for the Zubal voxel phantom is validated by the intercomparison of the results obtained by other Monte Carlo codes.
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spelling pubmed-54363162017-05-26 Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study Asl, Ruhollah Ghahraman Parach, Ali Asghar Nasseri, Shahrokh Momennezhad, Mehdi Zakavi, Seyed Rasoul Sadoughi, Hamid Reza World J Nucl Med Original Article The specific absorbed fraction (SAF) of energy is an essential element of internal dose assessment. Here reported a set of SAFs calculated for selected organs of a human voxel-based phantom. The Monte Carlo transport code GATE version 6.1 was used to simulate monoenergetic photons and electrons with energies ranging from 10 keV to 2 MeV. The particles were emitted from three source organs: kidneys, liver, and spleen. SAFs were calculated for three target regions in the body (kidneys, liver, and spleen) and compared with the results obtained using the MCNP4B and GATE/GEANT4 Monte Carlo codes. For most photon energies, the self-irradiation is higher, and the cross-irradiation is lower in the GATE results compared to the MCNP4B. The results show generally good agreement for photons and high-energy electrons with discrepancies within − 2% ±3%. Nevertheless, significant differences were found for cross-irradiation of photons of lower energy and electrons of higher energy due to statistical uncertainties larger than 10%. The comparisons of the SAF values for the human voxel phantom do not show significant differences, and the results also demonstrated the usefulness and applicability of GATE Monte Carlo package for voxel level dose calculations in nonuniform media. The present SAFs calculation for the Zubal voxel phantom is validated by the intercomparison of the results obtained by other Monte Carlo codes. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5436316/ /pubmed/28553177 http://dx.doi.org/10.4103/1450-1147.203065 Text en Copyright: © 2017 World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Asl, Ruhollah Ghahraman
Parach, Ali Asghar
Nasseri, Shahrokh
Momennezhad, Mehdi
Zakavi, Seyed Rasoul
Sadoughi, Hamid Reza
Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title_full Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title_fullStr Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title_full_unstemmed Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title_short Specific Absorbed Fractions of Internal Photon and Electron Emitters in a Human Voxel-based Phantom: A Monte Carlo Study
title_sort specific absorbed fractions of internal photon and electron emitters in a human voxel-based phantom: a monte carlo study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436316/
https://www.ncbi.nlm.nih.gov/pubmed/28553177
http://dx.doi.org/10.4103/1450-1147.203065
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