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Cannabinoid CB(1) and CB(2) Receptor Signaling and Bias

An agonist that acts through a single receptor can activate numerous signaling pathways. Recent studies have suggested that different ligands can differentially activate these pathways by stabilizing a limited range of receptor conformations, which in turn preferentially drive different downstream s...

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Detalles Bibliográficos
Autores principales: Ibsen, Mikkel Søes, Connor, Mark, Glass, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436336/
https://www.ncbi.nlm.nih.gov/pubmed/28861504
http://dx.doi.org/10.1089/can.2016.0037