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AT(1)-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers

BACKGROUND: Blockers of angiotensin II type 1 receptor (AT(1)R) and the voltage gated calcium channel 1.2 (Ca(V)1.2) are commonly used for treatment of hypertension. Yet there is little information about the effect of physiological concentrations of angiotensin II (AngII) on AT(1)R signaling and whe...

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Detalles Bibliográficos
Autores principales: Bernhem, Kristoffer, Krishnan, Kalaiselvan, Bondar, Alexander, Brismar, Hjalmar, Aperia, Anita, Scott, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436436/
https://www.ncbi.nlm.nih.gov/pubmed/28514967
http://dx.doi.org/10.1186/s12872-017-0562-x