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AT(1)-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers
BACKGROUND: Blockers of angiotensin II type 1 receptor (AT(1)R) and the voltage gated calcium channel 1.2 (Ca(V)1.2) are commonly used for treatment of hypertension. Yet there is little information about the effect of physiological concentrations of angiotensin II (AngII) on AT(1)R signaling and whe...
Autores principales: | Bernhem, Kristoffer, Krishnan, Kalaiselvan, Bondar, Alexander, Brismar, Hjalmar, Aperia, Anita, Scott, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436436/ https://www.ncbi.nlm.nih.gov/pubmed/28514967 http://dx.doi.org/10.1186/s12872-017-0562-x |
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