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Histone demethylases UTX and JMJD3 are required for NKT cell development in mice

BACKGROUND: Natural killer (NK)T cells and conventional T cells share phenotypic characteristic however they differ in transcription factor requirements and functional properties. The role of histone modifying enzymes in conventional T cell development has been extensively studied, little is known a...

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Detalles Bibliográficos
Autores principales: Northrup, Daniel, Yagi, Ryoji, Cui, Kairong, Proctor, William R., Wang, Chaochen, Placek, Katarzyna, Pohl, Lance R., Wang, Rongfu, Ge, Kai, Zhu, Jinfang, Zhao, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436453/
https://www.ncbi.nlm.nih.gov/pubmed/28529687
http://dx.doi.org/10.1186/s13578-017-0152-8