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In Vivo Cannabidiol Treatment Improves Endothelium-Dependent Vasorelaxation in Mesenteric Arteries of Zucker Diabetic Fatty Rats

Background and purpose: We have shown that in vitro treatment with cannabidiol (CBD, 2 h) enhances endothelial function in arteries from Zucker diabetic fatty (ZDF) rats, partly due to a cyclooxygenase (COX)-mediated mechanism. The aim of the present study was to determine whether treatment with CBD...

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Detalles Bibliográficos
Autores principales: Wheal, Amanda J., Jadoon, Khalid, Randall, Michael D., O’Sullivan, Saoirse E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436470/
https://www.ncbi.nlm.nih.gov/pubmed/28572770
http://dx.doi.org/10.3389/fphar.2017.00248