[(18)F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease

Microglial activation is a key pathological feature of Alzheimer's disease (AD). PET imaging of translocator protein 18 kDa (TSPO) is a strategy to detect microglial activation in vivo. Here we assessed flutriciclamide ([(18)F]GE-180), a new second-generation TSPO-PET radiotracer, for its abili...

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Detalles Bibliográficos
Autores principales: James, Michelle L., Belichenko, Nadia P., Shuhendler, Adam J., Hoehne, Aileen, Andrews, Lauren E., Condon, Christina, Nguyen, Thuy-Vi V., Reiser, Vladimer, Jones, Paul, Trigg, William, Rao, Jianghong, Gambhir, Sanjiv S., Longo, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436503/
https://www.ncbi.nlm.nih.gov/pubmed/28529627
http://dx.doi.org/10.7150/thno.17666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436503/
https://www.ncbi.nlm.nih.gov/pubmed/28529627
http://dx.doi.org/10.7150/thno.17666

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