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Novel Linear Peptides with High Affinity to αvβ3 Integrin for Precise Tumor Identification

Development of alternative linear peptides for targeting αvβ3 integrin has attracted much attention, as the traditional peptide ligand, cyclic RGD, is limited by inferior water-solubility and complex synthesis. Using pharmacophore-based virtual screening and high-throughput molecular docking, we ide...

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Detalles Bibliográficos
Autores principales: Ma, Yi, Ai, Guanhua, Zhang, Congying, Zhao, Menglu, Dong, Xue, Han, Zhihao, Wang, Zhaohui, Zhang, Min, Liu, Yuxi, Gao, Weidong, Li, Siwen, Gu, Yueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436510/
https://www.ncbi.nlm.nih.gov/pubmed/28529634
http://dx.doi.org/10.7150/thno.18401