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Synthesis of 5-[(18)F]Fluoro-α-methyl Tryptophan: New Trp Based PET Agents
Indoleamine 2,3-dioxygenase (IDO1) plays a special role in the biology of various cancer types, because it breaks down the essential amino acid tryptophan for immune cell activation. Upregulation of IDO1 significantly correlates with the number of various T cell types in tumor tissues in melanoma an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436511/ https://www.ncbi.nlm.nih.gov/pubmed/28529635 http://dx.doi.org/10.7150/thno.19371 |