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Synthesis of 5-[(18)F]Fluoro-α-methyl Tryptophan: New Trp Based PET Agents

Indoleamine 2,3-dioxygenase (IDO1) plays a special role in the biology of various cancer types, because it breaks down the essential amino acid tryptophan for immune cell activation. Upregulation of IDO1 significantly correlates with the number of various T cell types in tumor tissues in melanoma an...

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Detalles Bibliográficos
Autores principales: Giglio, Benjamin C., Fei, Haiyang, Wang, Mengzhe, Wang, Hui, He, Liu, Feng, Huijuan, Wu, Zhanhong, Lu, Hongjian, Li, Zibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436511/
https://www.ncbi.nlm.nih.gov/pubmed/28529635
http://dx.doi.org/10.7150/thno.19371