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Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1

AIMS: Remodelling of gap junctions, involving reduction of total gap junction quantity and down-regulation of connexin43 (Cx43), contributes to the arrhythmic substrate in congestive heart failure. However, little is known of the underlying mechanisms. Recent studies from in vitro systems suggest th...

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Detalles Bibliográficos
Autores principales:	Bruce, Alexandra F., Rothery, Stephen, Dupont, Emmanuel, Severs, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Originals
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436744/ https://www.ncbi.nlm.nih.gov/pubmed/18056766 http://dx.doi.org/10.1093/cvr/cvm083

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