The I(K1)/Kir2.1 channel agonist zacopride prevents and cures acute ischemic arrhythmias in the rat

Arrhythmogenesis in acute myocardial infarction (MI) is associated with depolarization of resting membraine potential (RMP) and decrease of inward rectifier potassium current (I(K1)) in cardiomyocytes. However, clinical anti-arrhythmic agents that primarily act on RMP by enhancing the I(K1) channel...

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Detalles Bibliográficos
Autores principales: Zhai, Xu-Wen, Zhang, Li, Guo, Yun-Fei, Yang, Ying, Wang, Dong-Ming, Zhang, Yan, Li, Pan, Niu, Yi-Fan, Feng, Qi-Long, Wu, Bo-Wei, Cao, Ji-Min, Liu, Qing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436763/
https://www.ncbi.nlm.nih.gov/pubmed/28542320
http://dx.doi.org/10.1371/journal.pone.0177600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436763/
https://www.ncbi.nlm.nih.gov/pubmed/28542320
http://dx.doi.org/10.1371/journal.pone.0177600

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