Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes

Oncolytic viruses which infect and kill tumour cells can also be genetically modified to express therapeutic genes that augment their anti-cancer activities. Modifying oncolytic viruses to produce effective cancer therapies is challenging as encoding transgenes often attenuates virus activity or pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Marino, Nalini, Illingworth, Sam, Kodialbail, Prithvi, Patel, Ashvin, Calderon, Hugo, Lear, Rochelle, Fisher, Kerry D., Champion, Brian R., Brown, Alice C. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436815/
https://www.ncbi.nlm.nih.gov/pubmed/28542292
http://dx.doi.org/10.1371/journal.pone.0177810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436815/
https://www.ncbi.nlm.nih.gov/pubmed/28542292
http://dx.doi.org/10.1371/journal.pone.0177810

Ejemplares similares