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MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth

Ewing Sarcoma is an aggressive, oncofusion-driven, malignant neoplasm of bone and soft tissue affecting predominantly children and young adults. Seeking to identify potential novel therapeutic targets/agents for this disease, our previous studies uncovered microRNAs regulated by EWS/Fli1, the most c...

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Detalles Bibliográficos
Autores principales: Moore, Colin, Parrish, Janet K., Jedlicka, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436853/
https://www.ncbi.nlm.nih.gov/pubmed/28542597
http://dx.doi.org/10.1371/journal.pone.0178028