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Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter

Cigarette smoking is the primary cause of chronic obstructive pulmonary disease (COPD) with repeated and sustained infections linked to disease pathogenesis and exacerbations. The airway epithelium constitutes the first line of host defense against infection and is known to be impaired in COPD. We h...

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Detalles Bibliográficos
Autores principales: Rao, Deviyani, Perraud, Anne-Laure, Schmitz, Carsten, Gally, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436865/
https://www.ncbi.nlm.nih.gov/pubmed/28542209
http://dx.doi.org/10.1371/journal.pone.0178021